This video provides a comprehensive overview of perinatal nicotine use, including the prevalence and risks associated with cigarette smoking, vaping and use of other nicotine products. The video also explores the role of screening and early intervention in identifying pregnant individuals using nicotine and connecting them with appropriate resources. Clinicians will learn about evidence-based smoking cessation strategies for pregnant and postpartum individuals, including the use of medication and behavioral interventions. The video also addresses the challenges of nicotine addiction and the importance of long-term support to maintain abstinence.